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Hello All
Could somebody suggest me some references which have PK-PD modeling
based on feed-back mechanisms. i.e., say we have two markers A and B
and the levels of A are dependent on the levels of B (based on
physiological mechanism). The drug has an effect on marker A.
Thanks in advance
Atul
Venkatesh Atul Bhattaram
Post-doctoral fellow
University of Florida
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The latest edition of the book by Gabrielsson and Weiner is a good source of
information about the feedback models.
Best regards,
Vladimir
Vladimir Piotrovsky, Ph.D.
Research Fellow
Advanced Modelling and Simulations
Global Clinical Pharmacokinetics and Clinical Pharmacology (ext. 5463)
Janssen Research Foundation
B-2340 Beerse
Belgium
Email: vpiotrov.-a-.janbe.jnj.com
PharmPK Discussion List Archive Index page
Copyright 1995-2010 David W. A. Bourne (david@boomer.org)