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We are working on a molecule which is currently being used as oral
dosage form for its systemic effect. The same drug also has topical
application too, and we are looking forward to develop a topical
formulation for its local effect.
We have oral PK parameters at its effective dose and we would like to
calculate topical dose. Are there any models to calculate topical
application dose based on its oral data.
I will appreciate your valuable inputs in this regard
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