CXT-a program for analysis of linear dynamic systems
A description provided by the author
CXT-a program for analysis of linear dynamic systems in
the frequency domain, written by Ladislav Dedik and Maria
Durisova, published in the International Journal of
Bio-Medical Computing 39, (1995) 231-241.
In this paper the computer program CXT-(CompleX Tools for
Linear Dynamic System Analysis), using the frequency
response method, is described and exemplified. The method is
based on the approximation of the frequency response of the
linear or linearised dynamic system, measured or calculated
from input-output measurements, by the frequency model of
the system transfer function in the form of the ratio of two
frequency-dependent polynomials. The form of the program
is sufficiently general to permit application in many areas,
e.g. in modeling linear or linearised pharmacokinetic
systems consisting of several subsystems arranged in serial
and/or parallel fashion, with or without time delays. The
program is a menu driven software taking data from
a keyboard or disk file to produce outputs on a screen,
printer, or disk file in tables and plots. The program can
run interactively or in an automatic tutorial mode, under
DOS and/or WINDOWS. Numerical examples are taken from
pharmacokinetics and indocyanine green liver function tests.
Until now, the program has been used in the following
papers:
- Dedik L and Durisova M: Frequency response method in
pharmacokinetics, J Pharmacokin Biopharm, 22 (1994) 293-307.
- Durisova and Dedik L: Comparative study of human
pentacaine pharmacokinetics in time and frequency domain,
Meth Find Exp Clin Pharmacol, 16 (1994) 219-232.
- Durisova, M., Dedik, L., Balan, M.: Building a structured
model of a complex pharmacokinetic system with time delay.
Bull Math Biol 1995, 57: 787-808.
Upon request, a version of the program will be sent
on receipt of a floppy in a self-addressed floppy disk
mailer.
Maria Durisova
Institute of Experimental Pharmacology,
Slovak Academy of Sciences,
842 16 Bratislava, Slovak Republic,
Phone/fax: 0042 7 375 928
e-mail: exfamadu@savba.savba.sk
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