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Could I have your kindness?
Dear all,
I have a Japanese undergraduate guest who is going to do pharmacokinetic
study of albendazole in rabbits. We have an albendazole product for
veterinary use. But we do not have standard materials of albendazole,
albendazole sulfoxide and albendazole sulfone. Is there its i.v.
formulation available? If yes, I would like to have one.Could I have
them in a very short time? I am also in position to buy them. Thanks in
advance.
Hyoin Yun, DVM, PhD
Professor of Vet. Pharmacol.
Faculty of Vet. Med., Chungnam National Univ.
220 Kung-dong, Yusong-ku, Taejon, Korea
Tel: +82-42-822-5780
Fax: +821-42-821-6759
e-mail: hiyun.-a-.hanbat.chungnam.ac.kr
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Dr. Yun,
To my knowledge there is no IV formulation available, at least not in the US
and I am 99% sure no where else. If memory serves, IV studies in the past
have been done with DMSO solutions. You should check the literature for
studies done by Quintin McKellar and others who have published extensively
in this area. I also believe that there has been some work with albendazole
and/or other benzimidazole anthelmintics in rabbits.
Hope this helps.
Rob Hunter
Dept. Veterinary Pharmacology
La State University
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Copyright 1995-2010 David W. A. Bourne (david@boomer.org)