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Dear list members,
I am looking for equations that describe the following steady state
conditions for oral dosing compartmental models:
Max Css for:
1 compartment (Cp) 1st order absorption & elimination;
Max Css, Min Css and Mean Css for:
Effect-site concentration (Ce) - 1 and 2 compartment, 1st order
absorption;
2-compartment (Cp) 1st order absorption model
I'd be grateful if anybody could point me in the right direction.
Regards,
Dyfrig
Dyfrig Hughes PhD
Department of Pharmacology & Therapeutics
University of Liverpool
Liverpool UK
L69 3GE
E-mail: dyfrig.-a-.liv.ac.uk
http://www.liv.ac.uk/prg
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Dyfrig,
Several of the equations you mentioned are described in the reprint
of the user guide for PK Solutions - the easy way to do
pharmacokinetics - located on our web site.
You can obtain the listing that includes some 75 equations at:
www.SummitPK.com
Regards,
David
David S. Farrier, Ph.D.
Summit Research Services
68911 Open Field Dr. Email: DFarrier.aaa.SummitPK.com
Montrose, CO 81401 Web: http://www.SummitPK.com
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Copyright 1995-2010 David W. A. Bourne (david@boomer.org)