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The following message was posted to: PharmPK
Dear All,
Hello!
What are the possible biological properties which can be related with
physicochemical parameters?
Please tell me some references too.
With regards,
Jyoti.
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They are not countable, just some examples:
C. Hansch, A. Leo, and D. Hoekman, Exploring QSAR, Vol. I and and
Vol. II, ACS
Professional Reference Book, Oxford University Press USA, New York
(1995)
(Embedded image moved to file: pic05545.pcx)
H. van de Waterbeemd, ed., Chemometric Methods in Molecular Design,
Vol. 2 in
Methods and Principles in Medicinal Chemistry, VCH, Weinheim (1995)
H.-D. Höltje and W. Sippl, eds., Rational Approaches to Drug
Design, Prous,
Barcelona (2001
P.W. Codding, ed., Structure-Based Drug Design: Experimental and
Computational
Approaches, Kluwer, Dordrecht, The Netherlands (1998)
Mager, Peter P., Multivariate chemometrics in QSAR (quantitative
structure-activity relationships) : a dialogue.
Letchworth, Hertfordshire, England : Research Studies Press ; New York
: Wiley,
c1988.
Harry
Dr. Harry Mager
Head Biometry & Pharmacometry
Bayer AG
BHC-PH-PD-GMD-GB Biometry & Pharmacometry
D-42096 Wuppertal / Bldg. 470
Telefon: +49 (0) 202-36-8891
Telefax: +49 (0) 202-36-4788
eMail: Harry.Mager.HM.-a-.Bayer-AG.de
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The following message was posted to: PharmPK
Jyoti:
The answer to your question (What are the possible biological
properties which can be related with physicochemical parameters?) is
really broad. A good resource is the web site of the QSAR and Modellig
Society (www.qsar.org), especially the section Resources - Books.
Stefan
Dr. Stefan Balaz
Associate Professor
North Dakota State University
College of Pharmacy
Department of Pharmaceutical Sciences
Sudro 8
Fargo, ND 58105
vox +1-701-231-7749
fax +1-701-231-7606
e-mail stefan.balaz.-at-.ndsu.nodak.edu
http://www.ndsu.nodak.edu/instruct/balaz
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