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Dear Colleagues
I am carrying out dissolution testing of Eudragit S 12.5 15% coated
beads
with (a) USP pH7.2 phosphate buffer and (b) BP pH7.2 Citrate/Phosphate
buffer. The dissolution profile using the USP phosphate buffer results
in an
exponential increase curve to plateau while the profile displayed with
BP
citrate/phosphate buffer displays a near linear concentration increase
curve. Can anyone suggest a reason for this?
Kind regards
Adrian MacRichard MRSC
ELAN Pharma
Athlone
Co. Westmeath
Ireland
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Copyright 1995-2010 David W. A. Bourne (david@boomer.org)