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The following message was posted to: PharmPK
Hi all
How do we go about calculationg the dose to be
administered in rabbits if we know the dose in mg/kg
of primates and rats. For example rat dose (mg/kg) is
twice the dose given to monkeys. I hope the question
is clear.
Any reference in this regard will be appreciated
Regards
Nitin
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Hi Nitin,
I hope the following website can help you
http://www.fda.gov/cder/cancer/animalframe.htm
Raj
Rajanikanth M
Post Doc Assoc
Pharmaceutics Division
University of Florida
Gainesville
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The following message was posted to: PharmPK
Hi Nitin,
you can calculate the dose (absolute) for rabbits
using the dose convertion table (depending on body
surface area). Refer Experimental pharmacology by M.N
Ghosh.
Hope this will help you.
SRINIVAS MUTALIK
RESEARCH SCHOLAR
COLLEGE OF PHARMACEUTICAL SCIENCES
MANIPAL-576119
KARNATAKA
PHONE
91-825-571201 EXT. 22122/22482
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