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Hi,
Free drug but not bound drug is responsible drug action in vivo. I read
this
theory is not completely applicable to highly protein bound antifungal
compounds such as itraconazole. Can some one share their experience on
in vivo
antifungal activity of highly protein bound drugs.
Thanks
Prasad
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Copyright 1995-2010 David W. A. Bourne (david@boomer.org)