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The following message was posted to: PharmPK
Dear Sir,
Kindly Attn : PharmPK,
I am working in Suven Life-sciences, a Pharmaceutical
Industry. We are working on Physico-Chemical
parameters
such as Aqueous solubility, Partition
coefficient(logP)
and Distribution coefficient(logD).
I need some reported values of Aqueous solubility,
logP and logD for following compounds:
1. Ciprofloxacin Hydrochloride
2. Atorvastatin Calcium
3. Cerivastatin
4. Clopidogrel Bisulphate
5. Nimesulide
6. Simvastatin
7. Lovastatin
8. Acetaminophene
9. Methyldopa
10.Citalopram.
Please try to send through mail at the earliest.
Thanking you.
With regards,
Srinivasulu Kota.
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The following message was posted to: PharmPK
Dear Srinu
look in this reference:
Molecular Properties of WHO Essential Drugs and
Provisional Biopharmaceutical Classification
Kasim, N. A.; Whitehouse, M.; Ramachandran, C.;
Bermejo, M.; Lennernas, H.; Hussain, A. S.; Junginger,
H. E.; Stavchansky, S. A.; Midha, K. K.; Shah, V. P.;
Amidon, G. L.;
Molecular Pharmaceutics; (Article); 2003; ASAP
Article; DOI: 10.1021/mp034006h
(http://pubs.acs.org/mp/)
and in these links:
http://esc.syrres.com/interkow/physdemo.htm
http://chemfinder.cambridgesoft.com/result.asp
hope this helps
Marival
Marival Bermejo
Assoc Prof. Pharmaceutics
Universidad de Valencia
Espaņa
http://www.uv.es/~mbermejo/absorption.htm
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