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Dear All
Can I get the information on Rosiglitazone -
Preclinical PK data.
Much literature is available on humans, but not in Rat or Mouse
So, Can any one provide this data.
Thanks
Sripal Reddy Mada
Sripal Reddy Mada, Ph.D
Research Scientist
Metabolic and Urology Group,
Ranbaxy Research Laboratories,
R & D - II, Plot no. 20, Sector 18,
Gurgaon, Haryana - 122 001, INDIA
Ph: +91-09818868128 (M)
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Well, you can go to CDER at this web address and download the Avandia
review that is posted. The pharmacology section will contain their
preclinical data.
http://www.fda.gov/cder/approval/index.htm
It is interesting to note that in the one animal efficacy study they
present, the results for rosiglitazone are not statistically
significant!
Cheers,
/Kevin P. Foley, Ph.D.
Associate Director, In Vivo Biology
Synta Pharmaceuticals Corp.
45 Hartwell Avenue
Lexington, MA 02421 USA
Tel: 781-541-7231
Fax: 781-274-8228
E-mail: kfoley.-at-.syntapharma.com
http://www.syntapharma.com
http://myprofile.cos.com/kpfoley
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