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Dear All,
In all B.E studies we consider median Tmax only.
Why we not considering mean Tmax in B.E calcuations.When we evaluate
the data of a B.E study for comparision of both Reference and Test
products for rate of absorption we should consider mean or median Tmax?
With Regards,
V.Radhakrishna
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The following message was posted to: PharmPK
We consider median Tmax, as Tmax is a discrete variable. Hence median
is more appropriate than mean.
Hope it helps,
Shilpi
Shilpi Khan, M.S.
Staff Scientist/Biostatistician
CEDRA Corporation
8609 Cross park Dr, Austin, TX 78754
[Tmax as in time of maximum measured concentration as compared with the
interpolated time of theoretical maximum concentration? - ok - db]
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