Back to the Top
I would like to calculate a definitive F-value from a variety of
preclinical rodent iv/po PK studies which all used the same compound,
routes and vehicles, but occasionally varied the dose (for example to
determine linearity). Is there a method which will enable me to
include all the po and iv AUCo-infinity values (every set of po
values has a corresponding group of iv data generated on the same
day) and doses to generate an 'all-data' F-value? Does anyone think
this is even a valid approach?
Dominic
[PopPK - db]
PharmPK Discussion List Archive Index page
Copyright 1995-2010 David W. A. Bourne (david@boomer.org)