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Dear all,
For carrying out Chromosomal Abberation Assay ( during drug
candidate selection) which cell line should be used - CHO / hamster
fibroblast / human fibroblast / human lymphocytes ?whether CHO will
give false negative results? what is the advantage of using
fibroblast rather than ovarian cell lines?
Thanking you in advance.
Regards
Dr.N.Fakrudeen.
Scientist II
DMPK lab,
TRC ,India.
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The following message was posted to: PharmPK
Hi:
I prefer human lymphocyte per ICH guideline.
Vuong Trieu PhD
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