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Dear All,
Can any one get me the ASTM procedures for equilibrium dialysis
method for protein binding studies.
2.Can any one suggest me the suppliers of single equilibrium dialysis
cell
I will be thankful for your valuable help.
Thanking you,
Yours Sincerely,
Subramanian
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I would recomment a 96 well teflon device. This is easy to handle,
with little adsoprption and allows for a relatiely high throughput.
You can get it from HTDialysis, Gales Ferry, CT, USA.
A refernce is:
[Banker MJ, Clark TH, Williams JA (2003)] Development and validation
of a 96-well equilibrium dialysis apparatus for measuring plasma
protein binding. J Pharm Sci; 92:967-74.
Best regards,
Markus
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The following message was posted to: PharmPK
We at Charles River Labs in Worcester routinely use the HT Dialysis
Teflon plate-based device and offer this as a service.
Howard Haspel,
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The following message was posted to: PharmPK
When the solubility of the molecule allows it, we classically use the
system of cells in teflon from DIANORM. And as CRO we realize as service
these studies.
Francoise BREE
DRUGGABLIS
France
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