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Hello;
I am a post graduate student in Addis Ababa University in the school
of pharmacy, ETHIOPIA
- I want to construct a dissolution profile for a drug. So, how
that profile could be constructed?
I want to construct % release of the drug versus time. I want to make
measurements at 20 30,40 minutes. How is then the % drug released
calculated so as to make the profile?
Many thanks for your consideration.
Getu k.
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The following message was posted to: PharmPK
Hi Getu
I don't know if your drug is formulated and if you want to
compare two diferents formulations ( a brand for market and test)
but, if it's immediate release form the times you intend make
the measurements is very limited, would be better in wich 2
minutes so that you do not loose datas from covered film,
if it's covered. In this case you should replace the medium in
which time you make a sampling to maintain the equilibrium
condition from de hydrodinamic system. Please let us more
information about your study.
Regards
Eldinaldo Sobral
Brazil
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