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The following message was posted to: PharmPK
The current release of POPT (ver 3; Release 20th Dec 2005) software
and user
and installation documentation for the evaluation and optimization of
population PK and PKPD studies can be downloaded now from...
http://www.uq.edu.au/pharmacy/sduffull/POPT.htm
POPT constitutes a set of programs written for MATLAB that can be
used for
optimization of nonlinear mixed effects models. POPT has been
specifically
written with population PKPD models in mind. Features of POPT include:
* Optimization for multiple response models (e.g. PK and PD data)
* Optimization for models defined as ODEs
* Optimization for multiple models (e.g. for 2 or more drugs
simultaneously)
* Optimization including some fixed sampling times, multiple study
arms,
for constrained clinic visit times, for lockout between consecutive
samples,
sampling windows, adding prior information.
This release supersedes previous releases (with hopefully fewer bugs).
Steve
=Stephen Duffull
School of Pharmacy, University of Queensland, Brisbane 4072, Australia
Tel +61 7 3365 8808, Fax +61 7 3365 1688, Email:
sduffull.aaa.pharmacy.uq.edu.au
www http://www.uq.edu.au/pharmacy/index.html?page=31309
Design: http://www.uq.edu.au/pharmacy/sduffull/POPT.htm
MCMC: http://www.uq.edu.au/pharmacy/sduffull/MCMC_eg.htm
University Provider Number: 00025B
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Copyright 1995-2010 David W. A. Bourne (david@boomer.org)