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Dear All,
Could anyone provide me information about plasma peak concentration
(Cmax) of oxcarbazepine after a single dose (600 or 800mg). I would
like to receive information about volume of distribution (Vd) of
oxcarbazepine, too.
It is possible to find out Cmax and Vd information about metabolite
(MHD) in the literature but not to oxcarbazepine.
If anyone has this information about a bioequivalence study (single
dose), it will be very nice.
Regards,
Daniel Rossi de Campos
Brazil
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Dear Daniel Rossi de Campos
Please see the details of oxcarbazepine and its metabolite for Cmax
only.
Mean(SD)Pharmacokinetic parameters.
Cmax of oxcarbazepine 4.26(1.44-S.D)nmol/g
Metabolite (MHD)- 25.48 (4.84-S.D)nmol/g
regrds
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Hi Daniel
Cmax for oxcarbazepine is 2780 ng/mL.
Regds
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Dear somesh and Gandhi
Please provide the reference for your parameter data (from where you
got these parameter values)
regards
PharmPK Discussion List Archive Index page
Copyright 1995-2010 David W. A. Bourne (david@boomer.org)