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Dear all,
I am searching for information regarding the distribution volume of
the midazolam metabolite, 1-hydroxy midazolam.
Can anyone tell me if there has been a PK analysis following 1-
hydroxy midazolam intravenous administration to rats (as the
likelihood of this information being available for humans is quite
low). Alternatively, the tissue to plasma partition coeffcients of 1-
hydroxy midazolam following midazolam administration would suffice.
Thanks,
Andrea
--
Andrea N. Edginton
Bayer Technology Services GmbH
Process Technology, Systems Biology
Bldg. E41, Rm 52
Leverkusen, Germany
Tel.: +49 (0)214/30-46034
Fax: +49 (0)214/30-64801
e-Mail: andreanicole.edginton.at.bayertechnology.com
http://www.bayertechnology.com
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Copyright 1995-2010 David W. A. Bourne (david@boomer.org)