Back to the Top
Hi.
Can someone guide me that for how long shall sampling in humans for
humanised monoclonal antibodies be done (half life approx 15-21 days
of humanised MAbs) to get an adequate data on PK parameters. No
animal data is available as none of the species is found sensitive
based on In vitro cross reactivity studies. We are planning to still
get toxokinetics data in one rodent and non rodent spieces. Will this
help?
It will be a great help.
Regards.
Shaloo
PharmPK Discussion List Archive Index page
Copyright 1995-2010 David W. A. Bourne (david@boomer.org)