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Dear All,
Could someone provide values about the tissue distribution of
lysosomes in rat?
It is well established that some organs (eg. lungs, liver, kidneys)
do have a high lysosomal content and are involved in ionic trapping
with basic drugs. I did find reference values for tissue content in
neutral lipids, phospholipids and all these, but nothing with respect
to lysosomes.
Regards,
Jean-Marie Nicolas
UCB S.A. Belgium
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