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The following message was posted to: PharmPK
Hi!
I am studying the enterohepatic circulation of RATS. In that regard,
I want to know the values of physiological concentrations of various
bile salts and their conjugates in various spaces (liver, bile duct,
intestine, systemic circulation, portal blood circulation and
sinusoidal space) of RAT. I also want to know the flow rates,
transport rates and biotransformation rates of the above 'from', 'to'
or 'in' various spaces (for RATS).
Please let me know the papers and web sites, which can provide me the
above information.
Regards.
Jyoti
--
Jyoti Bajpai Dikshit, Ph.D
Team Leader (Life Science)
Strand Life Sciences Pvt. Ltd.
Bangalore
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Hi Jyoti,
already mentioned on this forum, a good starting point in the review
by Kararli, Biopharm Drug dispos. Vol 16, 351-380 (1995).
regards,
Pascal
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The following message was posted to: PharmPK
Dear Jyoti,
There is some information on http://www.rivm.nl/interspeciesinfo/
under interspecies,
gallbladder, parameter list.
Or http://www.rivm.nl/interspeciesinfo/inter/gallbladder/ choose
parameters list.
Regards,
Jos Bessems
Jos GM Bessems, PhD (senior project manager)
Centre for Substances and Integrated Risk Assessment (SIR)
National Institute for Public Health and the Environment (RIVM)
PO Box 1, 3720 BA Bilthoven, The Netherlands
tel +31 30 274 4341 - fax +31 30 274 4475 - jos.bessems.-a-.rivm.nl
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