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Dear All
I need a clarification
I am working with Nifuroxazide it is insoluble in all medium and it
is a locally acting intestinal anti bacterial drug
If I want to compare the efficacy of our product in capsule with the
innovator product how can I compare?
We are already trying for Microbiological assay but we cannot perform
the test by filtration technique by other test, since it is an
antibacterial agent we need neutralizing medium but in none of the
neutralizing agent it is soluble please let me know how to proceed
for microbiological assay for this type of drug
(It is soluble in Dimethyl formamide and Alcohol but both DMF and
Alcohol are having antibacterial action)
Waiting for your valuable feed backs
With Warm Regards
Ram Kumar M.Pharm
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