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The following message was posted to: PharmPK
How does one calculate mean absorption time (MAT) for an oral drug in
the
absence of MRTiv data. Ordinarily, I believe MAT would be MRToral minus
MRTiv. I seem to recall seeing MRT represented as [Tlag plus 1
divided by
the oral absorption rate constant). Is this an acceptable approach?
Can you
use a Ka determined by the method of residuals for this purpose? Najib
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