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Dear All,
During a literature search i found two different gene protein related to efflux transporter, which is little bit confusing for me...
1) MDR-multi drug resistance.
2) MRP-multi drug resistance associated protein. What is difference between these two efflux protein?
Eagerly waiting for your valuable explanation.
Regards,
Rahul Vats
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Hi Rahul
The following is a very good review on transporters which you may find useful:
Ho and Kim (2005) Transporters and drug therapy: implications for drug disposition and disease. Clin Pharmacol Ther 78:260-277.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&d opt=Citation&list_uids=16153397
Regards
Masoud
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