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The following message was posted to: PharmPK
Does anyone know if there is a good commercial source for insects' CYPs?
Katya Tsaioun, Ph.D.
President
APREDICA
Contract research at the pace of discovery
313 Pleasant Street
Watertown, MA 02472
e-mail: Katya.-at-.Apredica.com
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Katya: Try contacting someone at the following sites:
http://p450.sophia.inra.fr/index_link.html
Most of the commercial vendors are selling baculovirus insect cells
transfected and manufacturing human p450. The site above is using
p450 from insects. You may need to prep this.
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Going back-do you need insect or baculosome cyp 450?
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Dear Katya Tsaioun,
I understand that, you need recombinant CYP450 enzymes which
expressed in insect cells. These will be available in commercially.
But if
you need really recombinant enzymes. I can suggest you to use CYP450
enzymes
which expressed in yeast which will work more or equal to insect system
CYP450 enzymes. These enzymes are economically also very convenient.
If you need any further information I can provide to you.
I look forward to your reply.
Thanks and Regards,
K.N.Purna chandra rao
Research Associate
PREMAS Biotech Pvt. Ltd.
Plot No. 77, Sector 4,
IMT Manesar.
Gurgaon-122050Haryana,
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