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Dear All:
Is there any guidance, scientific paper where we can find a
justification of the rational of log transformation of the cumulative
amount of drug excreted in urine Ae and the length of time (and
sampling times) for Bioequivalence studies employing urine instead of
plasma?
Best regards
Nelida Mondelo
R&D Manager
Nelida Mondelo - Investigacion y Desarrollo
Gador S.A.
Darwin 429 (1414CUI) - Buenos Aires - Argentina
www.gador.com.ar
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Dear Sir,
please check Applied biopharmaceutics and PK by Leon Shargel 5th
edition P 63-67
Dr zafar
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