PharmPK Discussion - Non-specific inhibitors for CYP and UGT in rats

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On 29 Nov 2009 at 21:54:52, "shiym" (shiym7.aaa.163.com) sent the message


Dear all
 I would like to find some drugs use as non-specific inhibitors for CYP  and UGT in rats respectively. Any informations will be much appreciated.  Thanks,
Yuming

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On 7 Dec 2009 at 03:24:40, Khalid Pasha (md_khalidp.-at-.yahoo.com) sent the message


Hi Yuming
You can use 1-aminobenzotriazole (1-ABT) as nonspecific CYP inhibitor in  rats. Unfortunately, i don't have information about nonspecific rat  UGT's.

Regards
Khalid

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