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Hello,
I am working in the field of bioequivalence ,I am facing some problems regarding the outlier detection when higher order crossover design in considered as a study design , I have consider many books but I didn't find the formulas for outiler detection for higher order crossover design If anybody have information about this so please inform me it will really appeciatied best regards Abdur Rasheed
Karachi
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Just the usual.
First, make sure that there are no post analytical errors-calculations, dilutions, juxtaposed digits, etc. Second, make sure that there are no pre-analytical errors- early or late visits, changes in dose, missed doses, doubled doses, incorrect group assignments. Third, after you have run those through, try Grubbs test or something similar-graph pad and minitab have some good programs for that application.
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