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The following message was posted to: PharmPK
Does any body knows Log P for Ziprasidone?
Thanks & Regards,
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The following message was posted to: PharmPK
Acccording to ADMET Predictor 4.0.0007:
Ziprasidone logP = 4.1
pKa = 9.6 acid and 6.8 base
So logD will range between 2-3 between pH 6 and 8
Best regards,
Walt Woltosz
Chairman & CEO
Simulations Plus, Inc. (NASDAQ: SLP)
42505 10th Street West
Lancaster, CA 93534-7059
U.S.A.
http://www.simulations-plus.com
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The following message was posted to: PharmPK
Dear Neha, please find the information required at
http://www.chemspider.com/
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The following message was posted to: PharmPK
Experimental Ziprasidone logP value according to the PhysProp, via
http://Drugbank.ca/
is 3.8
Best regards,
Sebastian
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Log P for Ziprasidone is 4.02 Log D at pH7.0 is 2.75 pKa 13.24 and 8.24
Ref: Wilson and Gisvold Text boox of organic, pharmaceutical and
Medicinal chemistry p 956
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