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Hi,
I am trying to learn optimal design using PFIM. It works well when I run optimization
using "simplex algorithm" everything is fine. However, if I run the same model using
"Fedorov-Wynn" I am getting the following error message.
Any suggestions how can I work on this problem
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Parameter using
Standard dose of 1000 mg oral dose running it as 1cp, V,Cl and Ka (76.91, 24.4,33.6)
Allowed sampling times (0.17, 0.33, 0.50, 0.67,0.83,1,1.5,2,3,4,5,6)
Max 2 and min 4 for allowed numbers of points be taken from each sampling interval
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Error message
***********
The Following objects(s) are masked from 'package:utils':
combn
Error in get(x):object'nwindA'not found
Calls:PFIM-> out.fedorov->lapply->FUN-.get
Execution halted
-
Kind Regards
Mouli
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