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The following message was posted to: PharmPK
Hi Everyone,
I am looking for animal models for conducting PK studies for novel oral
dosage
forms.
Does anyone have experience or reference for the following;
1. Monkey as a good predictive model for gastro-retentive tablet dosage
forms
2. Suitable model to evaluate effect of metallic ions e.g. chelation with Ca2+,
Mg2+ etc. present in small intestine on the permiability/absorption of a
drug
substance.
Any information or expertise available will be helpful.
Thanks
Anirudh
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