PharmPK Discussion List Archive - 2016

• Aldehyde Oxidase assay clearance calculation
• Calculation of number of animals needed
• eGFR calculation in children
• Enhanced bioavailability reduces variability
• Erythrocyte binding Kd and Bmax determination with scatchard plot
• Gender difference in CYP450 modulation in sprague-Dawley rats
• IC50 Value
• Illicit drugs and their metabolites in urine
• Intravenous Injection of Lipophilic drug - Very Lower Levels Detected
• Linear and nonlinear clearance in the same model
• Low Kp value but High concentration in the brain and blood
• Metabolite assay cross talk
• Method of residual
• Name the Drug, a pharmacy related app
• Nitrendipine intrasubject CV
• NONMEM practice data
• NONMEM table generation
• Paediatric predictions of CL for low Fa drugs
• Parallel absorption model
• Pharmacokinetic parameters to be evaluated for Multiphasic modified release drug product for EMEA submission
• PK analysis using different software
• Relationship between ka and Peff
• S9 Fraction reconstitution Buffer
• Single dose ER vs Multiple dose IR Drug-Which Tmax
• Small PK project
• Statistical method used in PK data analysis
• The quantification of S-amlodipine in human plasma
• tmax - Parent and Metabolite
• Unusual IV PK curve
• WinNONLIN Validation

Copyright 1995-2014 David W. A. Bourne (david@boomer.org)