PK/PD and Other Jobs

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Contact email address: - 23rd Mar 2023 [3136]

Postdoctoral position in Drug Metabolism and Pharmacokinetics group is available at The Johns Hopkins University with Johns Hopkins Drug Discovery (JHDD) The candidate will work with a multidisciplinary drugdiscovery team focused on the discovery and development of novel small molecule drugs in the areas of Neurology, Oncology, Gastroenterology, Ophthalmology, and Immunology. The individual selected will be responsible for the analytical method development (MS/MS), pharmacokinetic analyses, drug permeability analyses, drug metabolism (liver microsomes, S9, hepatocytes, etc.), and protein binding studies. In addition, he/she will be expected to also understand the absorption, distribution and elimination principles for application to the characterization of internal drug candidates. JHDD will provide a dynamic research environment including interactions with JHU faculty, medicinal chemists, biochemists, cell biologists and in vivo pharmacologists, as well as interaction with several Pharma industrial partners.
Requirements for the position include:

External website

Contact email address: - 22nd Mar 2023 [3135]

The University of Minnesota’s College of Pharmacy, Department of Experimental and Clinical Pharmacology (ECP) is seeking a faculty member who will complement our existing strengths in pharmacometrics by contributing field-shaping science to the areas of quantitative systems pharmacology, systems biology, disease modeling, methodological or computational skills related to pharmacometrics. This position aligns with the College of Pharmacy’s strategic plan to build expertise within the theme of precision medicine. Individuals will be expected to apply their pharmacometrics expertise to advance discovery and translation in precision medicine through development of innovative methodological tools and application of physiologic, pharmacokinetic and/or pharmacodynamic modeling.

Summary of Position:
The University of Minnesota’s College of Pharmacy, Department of Experimental and Clinical Pharmacology (ECP) invites applications for the position of Assistant or Associate Professor with a focus in Pharmacometrics. This is a 12-month, 1.0 FTE position. Successful candidates will possess an earned doctorate (e.g., Pharm.D., M.D., Ph.D.), and must have research experience that will enable them to establish a strong program of scholarly contributions to the field of pharmacometrics applied to clinical/translational research and precision medicine. The successful applicant will conduct research and teach professional pharmacy students and graduate students in the area of pharmacometrics. They will also provide service to department, collegiate and university initiatives and committees. The candidate will interact with members of other disciplines, schools, centers and research groups at the University to advance our capacity of making significant contributions to quantitative systems pharmacology.

About the Department:
The Department of Experimental and Clinical Pharmacology (ECP) is at the forefront of the emerging discipline of experimental pharmacotherapeutics, providing national and international leadership in individualized medicine through prominent research and an excellent graduate program. Groundbreaking and critical research is conducted in the Department of Experimental and Clinical Pharmacology. Our faculty are renowned experts in pharmacogenomics, neuropharmacology, drug metabolism, pharmacometrics, and specific therapeutic areas. Within the department, there is a diverse portfolio of supported research projects with funding from government, corporate, and foundation sources. Faculty members regularly present important findings at national and international conferences, lecture and collaborate across the country, and hold leadership positions in national organizations. Our graduate program offers M.S. and PhD degrees in an innovative, interdisciplinary program that trains students of the highest caliber to conduct research encompassing methodology from basic and clinical pharmacology perspectives. Additionally, ECP faculty contribute significantly to the education of pharmacy students in the College’s professional program through didactic instruction, laboratory experiences, clerkships and clinical rotations.

To view qualifications and apply, please visit:

External website

Contact email address: - 13th Mar 2023 [3134]

Our Client is searching for a director level pharmacometrics super star!

Our company actually placed the VP of PMx way back in 2008 and he is still there! The company has a robust pipeline with 25 clinical candidates, 7 approved products on the market-not to mention the 25 preclinical targets. I’ve included some info on the role below. Please let me know if you’d like to learn more. Thanks!

Represent clinical PK on clinical project teams and be responsible for all aspects of clinical PK and model informed drug development strategy and implementation for assigned projects Work closely with study team members including clinicians, translational scientists, regulatory, biostatisticians and etc. to provide pharmacometric deliverables on time Design and conduct pharmacometric analysis including population PK/PD analysis, PBPK modeling, simulation-based trial design and dose selection, author pharmacometric data analysis plans and reports, and communicate results to clinical teams and management in a timely manner

External website

Contact email address: - 2nd Mar 2023 [3133]

Associate Director role available in MA with global pharmaceutical client. Excellent pharmacometrics team and hiring manager. Multiple therapeutic areas for broad exposure.
Please email me at for more info. The Associate Director of Pharmacometrics is responsible for transforming non-clinical and clinical data into analyses that build the basis for MIDD of innovative drugs accessible to patients. The Associate Director will collaborate with cross-functional multidisciplinary teams and develop models to quantify and predict exposure-response relationships to inform optimal decision making on key development questions such as dose selection and trial design.
The ideal candidate will work independently to make decisions impacting M&S goals and to support the design, execution, and analysis of data emerging from clinical studies, will publish manuscripts and present at scientific conferences.

External website

Contact email address: - 3rd Feb 2023 [3131]

Cambridge Client is looking for Associate Director PK/PD Modeling and Simulations

Conduct PK/PD modeling of preclinical data and provide efficacious dose projections. Responsible for the modeling of early clinical data as appropriate. Design preclinical PK/PD studies in healthy and disease models. Develop and implement innovative, quantitative analyses and strategies for translational modeling across Discovery and Development projects. As a member of the DMPK team you will develop quantitative models and analyses to predict the DMPK characteristics of targeted protein degraders. Establish and maintain effective collaboration between biomarker, toxicology, pharmacology and DMPK scientists with the goal to predict safety margins, efficacious dose. Liaise with collaboration partners and CROs to generate data and models. Contribute to innovative and high quality publications and present data to external parties at conferences or meetings.

Please message me to learn more!

External website

Contact email address: - 2nd Feb 2023 [3130]

What: Summer Internship in Pharmacometrics. A paid PhD student level internship for 12-16 weeks.

Why: This is an exciting opportunity to get hands-on industry experience with mechanistic pharmacokinetic/pharmacodynamic (PK/PD) modelling and simulations for new drug modalities in the cardiovascular space. The graduate student intern will learn how to apply advanced statistical and computational methods to interpret preclinical data and interspecies translation at an early stage of drug development. The intern will have the opportunity to work closely with PK/PD scientists and modelers and will be exposed to the overall drug development process, other disease areas, clinical development teams and application of pharmacometrics in other therapeutic areas depending on interest.

Who: You are currently enrolled in a PhD program in a quantitative discipline, such as pharmacometrics, biostatistics, mathematics, or equivalent degree in the United States and have completed at least 2 years of study. Exposure to pharmacometric models, including population PK, PKPD, PBPK, and/or QSP models.  You have working knowledge of NONMEM and R. You are authorized to work in the United States.

Where: The Lilly Corporate Center in Indianapolis.

When: Start time is negotiable. Spring to fall is a great time to be in Indianapolis.

How: If interested, please submit your CV to Aurelie Lombard (, Jennifer Lang ( and Emmanuel Chigutsa (

Contact email address: - 10th Jan 2023 [3129]

Associate Director/Sr. Research Investigator/Research Investigator, PBPK

The scientist in this role will join an established Physiologically Based Pharmacokinetic (PBPK) modeling team with demonstrated and growing impact across the pipeline The individual will take on a variety of projects across therapeutic areas as well as preclinical and clinical development.

Please contact me at for more information.

External website

Contact email address: - 9th Jan 2023 [3128]

Sr Scientist/Principal Scientist/Associate Director Pharmacometrics role available--remote in the United States Client is a large pharma looking for someone with solid NONMEM experience that likes to work on diverse multicultural teams. This individual will conceive, execute and communicate multi-disciplinary modeling and simulations exercises to support development plans and strategies to achieve commercial goals and regulatory requirements for multiple functions. Generate new PK/PD modeling and simulation proposals and leads those efforts. Investigate, identify, develop, and optimize new methods and techniques in the field of PK/PD modeling and statistical data analysis. Leads Pharmacometric and PK/PD modeling aspects of multiple projects. Responsible for critically evaluating technical and scientific aspects along with Clinical Pharmacology and Pharmacometrics management. Lots of room for upward mobility and strong team mentorship to help you grow in your career both in technical aptitude and drug development expertise. As always, if not appropriate or of interest to you, please feel free to forward or send a referral. If you’d like to discuss please reply and we will set up a call.

Key Responsibilities:

Qualifications: Please contact me at for more info or call me at 315-415-4353. I have been retained.
Contact email address: - 5th Jan 2023 [3127]

Our Team

Sanofi Drug Metabolism and Pharmacokinetics (DMPK) research platform of the French Hub is seeking a highly motivated, enthusiastic experienced project expert mainly dedicated to support Immuno-Oncology and Molecular Oncology projects.

Main Responsibilities
As a member of the DMPK department the individual will be an integral project team member representing DMPK on biotherapeutics and small molecule research projects to ensure effective integration of ADME, PK and PKPD into the team strategy. This includes contributing to screening funnel designs to ensure appropriate ADME characterization, driving appropriate characterization of clinical candidates for regulatory submission, and preparing IND/IMPD/CTA regulatory submissions. This role will be responsible for working with all the experts of DMPK as well as on global DMPK workstreams. The successful incumbent will have expertise to support project teams across multiple therapeutic areas including Molecular Oncology, Immuno-Oncology and Rare and Neuro Diseases.

In this role he/she will contribute to the project team strategy at the early discovery phase up to first in human trials.

External website

Contact email address: - 2nd Jan 2023 [3126]

Dear colleagues,

At the French Agency for Food, Environmental and Occupational Health & Safety (France), we have an open postdoctoral research position in PK/PD and/or multimedia environmental modeling (MEM) of antimicrobials in the veterinary sector, for 18 to 24 months.

The postdoctoral position requires a doctoral (Ph.D. or equivalent) degree in PK/PD and or MEM. The applicant must have worked outside France (European or other country) for at least 18 months between May 2019 and the start of this project. French knowledge is not required.

Best regards
Dr. Alexis Viel DVM, Ph.D, ECVPT Resident EMAD Unit Anses- Fougères Laboratory 10 B rue Claude Bourgelat – 35306 FOUGERES Cedex

External website

28th Nov 2022 [3124]

Vir Biotechnology is a commercial-stage immunology company focused on combining immunologic insights with cutting-edge technologies to treat and prevent serious infectious diseases. Vir has assembled four technology platforms that are designed to stimulate and enhance the immune system by exploiting critical observations of natural immune processes. Its current development pipeline consists of product candidates targeting COVID-19, hepatitis B virus, influenza A and human immunodeficiency virus.

We believe the success of our colleagues drives the success of our Mission. We have an ongoing commitment to creating a company passionate about equality, inclusion, and respect. When everyone feels supported and encouraged to give at their best, we will collectively deliver outstanding results.

Vir Biotechnology is seeking a Clinical Pharmacologist to support of all phases of drug development for from early clinical development, market application, and commercialization.


QUALIFICATIONS AND EXPERIENCE: Vir’s compensation and benefits are aligned with the current market and commensurate with the person’s experience and qualifications. All full-time employees receive a package that includes: compensation, bonus and equity as well as many other Vir benefits and perks such as: health, dental, vision, life and disability insurance benefits, non-accrual paid time off, one Friday a month paid-time off, company shut down for holidays, commuter benefits, child care reimbursement, education reimbursement, 401K match and lunch for all lab essential personnel!

Vir is an equal opportunity employer. We value diversity at our company. We do not discriminate on the basis of race, religion, color, national origin, sex, gender, gender expression, sexual orientation, age, marital status, veteran status, or disability status. We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform critical job functions, and to receive other benefits and privileges of employment. Please contact Human Resources to request accommodation.

Vir Human Resources leads recruitment and employment for Vir. Unsolicited resumes sent to Vir from recruiters do not constitute any type of relationship between the recruiter and Vir and do not obligate Vir to pay fees should we hire from those resumes. We ask that external recruiters and/or agencies not contact or present candidates directly to our hiring manager or employees.

External website

Contact email address: - 18th Nov 2022 [3123]

Contact: -

Job title: Pharmacometrician / Pharmacokinetic Modeller

Location: The London Cancer Hub’s Innovation Gateway in South West London (Sutton).

Contract type: Full-time, permanent

About Vesynta: We are developing a toolkit that, for the first time, will enable clinicians dosing life-saving therapies (incl. chemotherapies, antibiotics and immunosuppressants) to map the unique pharmacokinetics of their patients at the point of-care using this information to rapidly identify the optimal dose, for each and every patient. Having spun-out of University College London, we work with clinicians, patients and academics across the UK, Europe and the USA, to establish this important healthcare innovation into clinical practice. Our work has been recognised and awarded for its vision and impact, including funding from prestigious grant competitions (Innovate UK, NIHR i4i) and private equity. We welcome you to join our journey to deliver data-guided dosing, that is safe, effective, and personalised to every patient.

Role description: You will operate within the clinical pharmacology division of the R&D team. It involves applied pharmacometrics including population pharmacokinetic (PK) and pharmacodynamic (PD) modelling building on exposure-response datasets. Your models form an integral part of our clinical software solution that will deliver personalised treatments in clinical practice. Support will be provided by senior team leads, internal clinical advisors and collaborators from globally renowned research institutions. This will aid your decision making and data interpretation, applied to real-world patients across a variety of disease areas. You will have the opportunity to lead pharmacometrics processes and techniques within the team, combined with strategic business exposure, to develop models for both product development and guide use-case prioritisation. You will work alongside our software developers to ensure your models are useable and scalable.

Key responsibilities:

Candidate experience: Essential: Application
Point of contact: Dr Jugal Suthar
How to apply: Please email us your CV and motivations for applying to, including the following reference: “VS-005344-HR” to begin the conversation.
Closing date: 09 January 2023
Links to full posting:

External website

Contact email address: - 13th Nov 2022 [3122]

Dear colleagues,

At the University of Bonn, Germany, we have an open postdoctoral research position in Pharmacometrics for 3 years.

The position is part of a cooperation of our Department of Clinical Pharmacy with the Federal Institute for Drugs and Medical Devices (BfArM) in Bonn which is the national authority for the approval and safety of drugs in Germany. Therefore, this position is particularly attractive for pharmacometricians with interest in academia and regulatory affairs. It offers career opportunities in both directions.

The postdoctoral position requires a doctoral (Ph.D. or equivalent) degree in pharmacometrics. German knowledge is not required.

Please find further information on the position under the following link:

Best regards Ulrich Jaehde
Prof. Dr. Ulrich Jaehde Institute of Pharmacy University of Bonn An der Immenburg 4 D-53121 Bonn
Tel.: +49-228-735252 Fax: +49-228-739757 E-Mail:

External website

Contact email address: - 27th Oct 2022 [3121]

Postdoctoral Fellow and Ph.D. students Opportunity One Postdoctoral position is available at the group of Dr. Zhu Zhou at York College of the City University of New York (CUNY) and The CUNY Graduate Center to work on the research project funded by NIH. The postdoctoral fellow will conduct research that supports understanding of pharmacokinetics and pharmacodynamics in special/disease populations and enables precision dosing. The postdoctoral fellow will be initially appointed for a year-long term. The position is renewable for another year with the possibility of an extension, with an anticipated start date of Feb 2022 (negotiable). The candidate should be highly motivated and able to work well independently and have excellent communication skills. The ideal candidate should have a strong interest in model-informed precision dosing, pharmacometrics approaches to optimize pharmacotherapy. Applicants in related fields are encouraged to apply.

Duties and responsibilities:

  1. Doctorate (PhD, PharmD, MD, or DVM) in pharmaceutical sciences, pharmacokinetics, pharmacology, pharmacodynamics, or relevant field.
  2. Good track record of productive research and publications.
  3. Demonstrated proficiency in written and oral communication skills.
  4. Excellent organizational and interpersonal skills.
  5. Ability to work independently on assigned projects.
  1. Experience with pharmacokinetics/pharmacodynamics modeling and simulation and related software packages
  2. Experience with pre-clinical and clinical studies
To apply, please submit these three documents listed below to Dr. Zhou by email: 1) Current CV 2) A brief statement of research experience, interests, and career goals 3) The names and contact information of the three references This position will remain open until filled.

Dr. Zhou's lab also has 1-2 Ph.D. student positions. This is open to candidates with a university degree in pharmacy, pharmaceutical sciences, biochemistry, biostatistics, bioinformatics, life sciences, or medicine. See for how to apply for the Ph.D. program.
Interested candidates can submit a cover letter, CV, as well as names and contact information of three references to Dr. Zhou by email:

Contact email address: - 19th Oct 2022 [3120]


MMV is a Swiss non-profit foundation whose mission is to reduce the burden of malaria in disease-endemic countries by discovering, developing and delivering new, effective and affordable antimalarial drugs. Working with drug discovery/development partners in academia and industry, as well as with country-based delivery partners and national ministries of health/malaria control programmes, MMV’s focus extends from the identification of new potential treatments for malaria through to clinical development, regulatory approval and delivery-for-impact in malaria-endemic countries. Since its founding in 1999, MMV and partners have brought forward 11 new medicines that have saved an estimated 2.7 million lives.

We are currently seeking a PKPD postdoc to join our Pharmacometrics team. We are seeking a highly motivated individual who will provide scientific expertise in PKPD modelling as well as modelling and simulation strategy.



  • Ph.D. in Biomedical Science, Pharmacy, Clinical Pharmacology, Biometrics or Computational Engineering
  • 2 years of post-doctorate experience (academia and/or industry) with a proven track record within the duties mentioned above
  • Published peer-reviewed articles
  • Familiarity with the drug development process is an asset
  • Experience working in a cross-functional matrix is also an asset
  • START DATE: As soon as possible

    DEADLINE: November 16, 2022


    External website

    Contact email address: - 17th Oct 2022 [3117]

    Working at Horizon is more than a job – it’s personal. For us, success is measured by the numbers that matter most – the number of lives we touch, the number we change and those we work tirelessly to help save. We’re a team of agile, out-of-the-box thinkers who are inspired to do more because we know we’re a part of something bigger. We strive to build meaningful careers at a company whose values we share because when we live up to our potential, we help others live up to theirs.


    Qualifications and Skills Required:

    External website

    Contact email address: - 27th Sep 2022 [3116]

    Modelling scientist/specialist/principal scientist

    Do you wish to be a part of our modelling team focusing on pharmacokinetics (PK) and pharmacodynamics (PD) from clinical studies? Can you help us in guiding decisions in clinical drug development using clinical trial simulations? If so, then you could be a part of our growing area!

    We are hiring for several positions within the Pharmacometrics department at Novo Nordisk. Several locations are available across the globe (Copenhagen, Madrid, Boston, etc).

    Novo Nordisk has a clear purpose of driving change to defeat diabetes and other serious chronic diseases. To support this, a new Data science organisation has been established in which Pharmacometrics is anchored. Our vision is to ensure Novo Nordisk is a global healthcare leader powered by data, analytics, and digital technologies. We are therefore looking for strong modelling scientists to help us reach our goals.

    Deadline for applications: 16 October 2022

    Please note, that screening and interview will be done on an ongoing basis.

    External website

    Contact email address: - 26th Sep 2022 [3115]

    Vir is a science-driven company guided by medical need. Vir integrates diverse innovations in science, technology, and medicine to transform the care of people with serious infectious diseases. Vir is taking a multi-program, multi-platform approach to applying these breakthroughs, including the development of treatments that induce protective and therapeutic immune responses. Vir’s scale and scope together with leading scientific and management expertise, allow it to perform significant internal R&D, in license or acquire innovative technology platforms and assets, and fund targeted academic research.

    Primary job includes uploading data from in vitro and in vivo DMPK studies, tracking outsourced assays, assisting in lab supply management and ordering. High throughput assay experience a plus. You will work within a highly collaborative group focused on infectious disease research. Candidates should have experience working in a laboratory research setting.


    QUALIFICATIONS AND EXPERIENCE: EDUCATION: VIR is an equal opportunity employer and strictly prohibits unlawful discrimination based upon an individual’s race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, mental/physical disability, medical condition, marital status, veteran status, or any other characteristic protected by law.

    The Human Resources team manages the recruitment and employment process for Vir. Unsolicited resumes sent to Vir from recruiters do not constitute any type of relationship between the recruiter and Vir and do not obligate Vir to pay fees should we hire from those resumes. Recruiters are requested not to contact or present candidates directly to our hiring manager or employees.

    External website

    Last update: Thu 23 Mar 2023 06:25:43 pm

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