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The following message was posted to: PharmPK
Dear group,
I have got a question about metacholine PK from a group that plans give it
IV as part of a procedure to test endothelial cell dysfunction (in aorta). I
have searched for basic PK data but can not find much . Can any of you help
me out ? I assume that there will be a substantial "first pass" metabolism
in the lung circulation?
Regards
Nils Ove Hoem
Dept. Pharmacol. School of Pharmacy
University of Oslo
Norway
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