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hi team
heres a query related to the pharmacokinetics of iron absorption.
it has been observed that the route of iron absorption when iron is
administered
through protien complexes (ie iron polymaltose,iron dextran,iron
polysaccharide
etc) is markedly different from that if given in the conventional form (ie
fumarate,gluconate ,or other salts)
i fail to comprehend why ??and which are these two different routes??
also please let me know if the fact that heme iron is absorbed better from the
intestine compared to non heme iron,has got anything to do with the fact that
iron protein complexes seem to have a better bioavailabilty (since heme is a
protein too!!!) .Are there any other factors??
i really need this clarifications for my design of pk study!!!!!!
help!!
dr gauri tare
(Gaurikulkarni.at.sunmumb.spil.sprintsmx.ems.vsnl.net.in)
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Copyright 1995-2010 David W. A. Bourne (david@boomer.org)