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I'm a pH Doctor student and I work with pharmakokinetic profile of
NSAIDs in plasm and limph. I have problems with piroxicam
determination by HLPC method in plasm. Anybody can help me?
Thanks.
M.I. Toledo
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[Three replies - db P.S. I have turned off MIME again]
Mime-Version: 1.0
Date: Fri, 15 Jan 1999 09:18:53 -0500
To: PharmPK.at.pharm.cpb.uokhsc.edu
From: shoaf.-a-.clinpharm.niaaa.nih.gov
Subject: Re: PharmPK piroxicam determination
>I'm a pH Doctor student and I work with pharmakokinetic profile of
>NSAIDs in plasm and limph. I have problems with piroxicam
>determination by HLPC method in plasm. Anybody can help me?
>Thanks.
>
>M.I. Toledo
Can you be more specific? Is your problem separation, recovery, sensitivity?
A quick Medline search turned up 8 different published methods in rat or
human blood. Have you compared these different reports?
Susan Shoaf, Ph.D.
Acting Chief, Unit of Pharmacokinetic Studies
NIAAA
---
X-Sender: gleader.at.wvuhsc1.hsc.wvu.edu
Date: Fri, 15 Jan 1999 10:53:03 -0500
To: PharmPK.aaa.pharm.cpb.uokhsc.edu
From: "W. Greg Leader"
Subject: Re: PharmPK piroxicam determination
Cc: ttracy.at.wvu.edu
Mime-Version: 1.0
Suggest you email Tim Tracy at West Virginia University School of
Pharmacy. He has a lot of experience with the NSAIDs and may be able to
help you. His email is ttracy.at.wvu.edu.
---
Date: Fri, 15 Jan 1999 10:29:15 -0700 (MST)
From: Delwar Hussain
Subject: Re: PharmPK piroxicam determination
X-Sender: delwar.at.ASUWlink.uwyo.edu
To: PharmPK.-a-.pharm.cpb.uokhsc.edu
MIME-version: 1.0
I am using a modified method of Boudinot et al. 1993, J Pharm Sci,
82:254-257 to determine piroxicam in plasma. Hope this helps. If you need
further information let me know.
Delwar
********************************************************************************
M. Delwar Hussain, Ph.D.
Assistant Professor of Pharmaceutics
School of Pharmacy
University of Wyoming
Laramie, WY 82071-3375
Tel:(307) 766 6129
Fax: (307) 766 2953
E-mail: delwar.at.uwyo.edu
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