PharmPK Discussion List Archive - 1997

PharmPK Discussion List Frequently Discussed Topics

3 Questions and 1 Suggestion
Abbott-Base program
About Newman-Keuls or Student Newman-Keuls test; Thanks!
Absorption rate constant
ACCP Pharmacokinetics Group
ADAPT II (Ver 4.0)
Adjusted weight-based dosing for LMWHs?
Adsorption of lipophilic drug to polycarbonate membrane
Altered PK by solid tumor properties
Aminoglycoside dosing in critical care
Aminoglycosides and subcutaneous route
Amiodarone Pharmacokinetics
Amphetamine metabolism
Anaesthtic Effects of Tricaprylin
Analytical method for metimazol
Analyzing three compartment models
ANOVA for comparison of bioavailabilities
Antimicrobial Pharmacokinetics in the Eye
Antimineralocorticoids
Apparent Bioavailability in Excess of 100%
Apparent volume of distribution of a drug eliminated only by
AUCt, AUCinfinity
Biliary excretion
Bioavailability
Blood flow - Perfusion
Blood Volume
Book
Calculation of F and PK/PD Modeling
Cardene SR
Ceftriaxone PK in children
Chemistry 4D-Draw experience
Clinical Issue - vancomycin/gentamicin
Collinearity and mixed effect models
Compartmental Modeling and Pop PK
Consensus documents
Creatinine Clearance & IBW in Patients that are "Small"
Cyclophosphamide
Depot formulation
Detection of Lactoferrin
Determining CYP3A4 activity in vitro
Digital Visual Fortran and NONMEM
Digoxin guidelines
Diltiazem PK
Dilution Effect of Neuromuscular blockers
Dissolution test for nicardipine HCl TABLET
Dosage
Dose determination
Drug Interference Testing
Drug use in CVVH and CVVHD
Dry Lab HPLC software.
EC50
Effects of dilution on PK/PD of nondeploarizing neuromuscular
Erratum
Exaprolol
Experience with MATLAB
Exponential Fitting vs. Compartmental Modeling
First Dose in Man
First-order one compartment formulas
Fluoroquinolone absorption w/ enteral feedings
Gabapentin (Neurontin) use in diabetics
Gerontokinetics
Grapefruit juice-drug interaction warnings
Graphic Interface
Help
Help with unusual pk problem
Hi/Lo Extraction Drug Info
High throughput PK
History of PK
How are tumor drug concentrations measured?
Humulin R Insulin
Ideal Body Weight Calculations
In Vitro to In Vivo scaling for metabolic parameters
Infusion rate vs Concentration
Interactive Pharmacokinetic teaching
Interspecies scaling of lung surface area
Intracellular PK
Isometheptene pharmacokinetics
IV Cannulas in Rats
IV Drug Delivery System?
IVIV Correlation Recommendations
Jack Knife Mean
ka/k values for immediate release formulations
Ketamine pharmacokinetics
Ketanserin
Ki inhibitor constant (part II)
Ki, inhibition constant
Kinetica 2.0 Release Date
Levodopa Concentration Fluctuations
Lipid suppliers
List of Noncompartmental PK Equations
Log P software for peptides
Log trapezoidal rule
Long term cannula in rats
Looking for pK data that requires a log transformation
Mecamylamine
Median and Mean
Metabolite-HPLC standard
Micromath's PKAnalyst
Modeling vs non-compartmental PK Analysis
Nephrotoxicity of antimicrobials
Netilmicin pharmacokinetics in neonates
Network thermodynamic simulations of kinetic models
New book version
New Book- HPLC of Pharmaceuticals
New Kinetic Modeling and Computational Biology Forum
New software for population PK/PD
News
News on Visual-NM
NM-WIN
NONMEM Courses
NPML-fit
NSAID patches
Occupational Benzene Exposure
ODA aminoglycosides
Once a day dosing
Once Daily Aminoglycosides in Kids
Oral scopolamine
Ototoxicity
PCs-my of literature articles-what is best?
Pediatric dosing
Pediatric PK reference
Perfused Rat Kidney
Permeability and Bioavailability
Pethidine/meperidine pharmacokinetics
Pharmacokinetic Imaging
Pharmacokinetic Software for Windows 95
Pharmacokinetics in children
Pharmacokinetics modeling
Pharmacokinetics of Maleic Acid
Pharmacokinetics textbook
Phenobarb pretreated rats
Physiologic-PK modeling in UG course
Physiological change with age
Physiological Modelling
PK Imaging
PK market
PK Software
PK Solutions 2.0 Demo Update
PK Textbooks
PK-PD of Oral Hypoglycaemics
PK/PD Books
Plasma NO
Plasma/blood volume ratio
Poor permeability but high absorption?
Population Pharmacokinetics and Bayesian Forecasting in Neonates
Potassium Chloride orders
Prednisolon interaction
Probenecid
Procainamide
Procainamide Pharmacokinetics in Neonates
Protein binding
Prozac drug interactions
Pulmonary clearance
Quantitation of NO in plasma
Questions
Questions on cyclosporin and D-penicillamine
Quinolones and Enteral Feedings
R-Verapamil and S-Verapamil standards
Radiolabelled Polymyxin B
Rat kidney perfusion
Reduced glutathion
Regarding highly lipophilic compounds
Request for Information
RMSE
S-oxide metabolite analysis
SAAM II Modeling
Scaling
Scanning Plots
Searching Guidelines on bioequivalence and PK
Second consensus document available
Sepsis-induced acute lung injury
Simulation with Pharsight Trial Designer
Software Recommendation?
Source for Tamoxifen metabolites?
Stability of amine drug N-oxides
Statistical analysis in ANOVA
Statistical Inferences
Systemic infection (Sepsis,
Tertiary butyl alcohol
Textbooks
The estimation of AUMC
Therapeutic effects of administration of placebos
Thioacetamide and its metabolites
Tissue distribution of organic anion transporter
TK data and LOQs
TK data: Commentary
Tobramycin detection
Tobramycin in tissue
Tobramycin stability in plasma
TOPFIT query
Topically applied Nitrolingual Spray
Tramadol - Drug interactions?
Transgenic animals in PK
Updated ODA consensus document.
Using computer-assisted technology to optimize clinical trial
USP DMSO
Vancomycin dosing
Vancomycin extended interval dosing
Vancomycin pre and post level
Vancomycine pk
VCM monitoring
Vd for Vancomycin from Literature
Very high plasma clearance
VIS SIM and other compartments
What should we call the amount of a drug that reaches its target
Where are Global Minima in Curve-Fitting?
Where Is The Science In Once-Daily Aminoglycosides ?
WinNonlin pkin model

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